Researchers of Jefferson’s Kimmel Cancer Center have produced genetic evidence suggesting antioxidant drugs could help prevent and treat cancer. With research already showcasing the powers of various cancer fighting foods, this research further shows how dangerous mainstream medical testing and treatments can be outranked by nature’s gifts.
“Antioxidants have been associated with cancer reducing effects—beta carotene, for example—but the mechanisms, the genetic evidence, has been lacking,” says lead researcher Michael P. Lisanti, M.D., Ph.D. “Now we have genetic proof that mitochondrial oxidative stress is important for driving tumor growth.”
Oxidative Stress and Tumor Growth
Lisanti’s study shows that loss of the tumor suppressor protein Caveolin-1 (Cav-1) stimulates mitochondrial oxidative stress in the stromal micro-environment. If this is Greek to you, let’s put it this way: if a woman has breast cancer and has the biomarker Cav-1, she has greater chances of survival than someone who doesn’t have the Cav-1 protein. The loss of the protein, in fact, leads to oxidative stress, thereby quadrupling in tumor mass and volume with no increase in tumor angiogenesis.
That’s where antioxidants step in.